Cargando…
The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline
The switch from mitosis to meiosis is the key event marking onset of differentiation in the germline stem cell lineage. In Drosophila, the translational repressor Bgcn is required for spermatogonia to stop mitosis and transition to meiotic prophase and the spermatocyte state. Here we show that the m...
Autores principales: | Bailey, Alexis S, Batista, Pedro J, Gold, Rebecca S, Chen, Y Grace, de Rooij, Dirk G, Chang, Howard Y, Fuller, Margaret T |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703642/ https://www.ncbi.nlm.nih.gov/pubmed/29087293 http://dx.doi.org/10.7554/eLife.26116 |
Ejemplares similares
-
YTHDC2 serves a distinct late role in spermatocytes during germ cell differentiation
por: Bailey, Alexis S., et al.
Publicado: (2023) -
YTHDC2 control of gametogenesis requires helicase activity but not m(6)A binding
por: Saito, Yuhki, et al.
Publicado: (2022) -
ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2
por: Jain, Devanshi, et al.
Publicado: (2018) -
Conservation of oocyte development in germline cysts from Drosophila to mouse
por: Spradling, Allan C, et al.
Publicado: (2022) -
m(6)A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2
por: Mao, Yuanhui, et al.
Publicado: (2019)