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Structural basis for TNA synthesis by an engineered TNA polymerase

Darwinian evolution experiments carried out on xeno-nucleic acid (XNA) polymers require engineered polymerases that can faithfully and efficiently copy genetic information back and forth between DNA and XNA. However, current XNA polymerases function with inferior activity relative to their natural c...

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Detalles Bibliográficos
Autores principales:	Chim, Nicholas, Shi, Changhua, Sau, Sujay P., Nikoomanzar, Ali, Chaput, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703726/ https://www.ncbi.nlm.nih.gov/pubmed/29180809 http://dx.doi.org/10.1038/s41467-017-02014-0

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