Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report

Warfarin induced skin necrosis (WISN) is a rare but important side effect of warfarin. Early diagnosis may lessen the amount of permanent tissue damage and can prevent progression to full thickness skin necrosis. So, physicians should be aware of such a complication. Screening for protein C or S or...

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Autores principales: Mahdizadeh, Fatemeh, Safari, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Beheshti University of Medical Sciences 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703748/
https://www.ncbi.nlm.nih.gov/pubmed/29201953
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author Mahdizadeh, Fatemeh
Safari, Saeed
author_facet Mahdizadeh, Fatemeh
Safari, Saeed
author_sort Mahdizadeh, Fatemeh
collection PubMed
description Warfarin induced skin necrosis (WISN) is a rare but important side effect of warfarin. Early diagnosis may lessen the amount of permanent tissue damage and can prevent progression to full thickness skin necrosis. So, physicians should be aware of such a complication. Screening for protein C or S or anti-thrombin deficiencies, or presence of anti-phospholipid antibodies before beginning warfarin therapy, could be helpful to avoid high levels of international normalized ratio (INR). Here, we report a 54-year-old man who presented to the emergency department with acral and penile gangrene following prolonged use of warfarin.
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spelling pubmed-57037482017-11-30 Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report Mahdizadeh, Fatemeh Safari, Saeed Emerg (Tehran) Case Report Warfarin induced skin necrosis (WISN) is a rare but important side effect of warfarin. Early diagnosis may lessen the amount of permanent tissue damage and can prevent progression to full thickness skin necrosis. So, physicians should be aware of such a complication. Screening for protein C or S or anti-thrombin deficiencies, or presence of anti-phospholipid antibodies before beginning warfarin therapy, could be helpful to avoid high levels of international normalized ratio (INR). Here, we report a 54-year-old man who presented to the emergency department with acral and penile gangrene following prolonged use of warfarin. Shahid Beheshti University of Medical Sciences 2017 2017-06-21 /pmc/articles/PMC5703748/ /pubmed/29201953 Text en © Copyright (2017) Shahid Beheshti University of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mahdizadeh, Fatemeh
Safari, Saeed
Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report
title Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report
title_full Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report
title_fullStr Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report
title_full_unstemmed Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report
title_short Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report
title_sort concurrent hand and penile gangrene following prolonged warfarin use; a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703748/
https://www.ncbi.nlm.nih.gov/pubmed/29201953
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