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Stabilizers of edaravone aqueous solution and their action mechanisms. 1. Sodium bisulfite

Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) has been used as a free radical scavenging drug for the treatment of acute ischemic stroke in Japan since 2001. Edaravone is given to patients intravenously; therefore, it is distributed in the form of an aqueous solution. However, aqueous solutions of...

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Detalles Bibliográficos
Autores principales:	Tanaka, Masahiko, Sugimura, Natsuhiko, Fujisawa, Akio, Yamamoto, Yorihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	the Society for Free Radical Research Japan 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703788/ https://www.ncbi.nlm.nih.gov/pubmed/29203955 http://dx.doi.org/10.3164/jcbn.17-61

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