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Cancer cell-specific mitochondrial reactive oxygen species promote non-heme iron uptake and enhance the proliferation of gastric epithelial cancer cell
Iron is an essential nutrient for life and is involved in many important processes such as oxygen transport and DNA synthesis. However, excess amounts of iron can cause carcinogenesis by producing reactive oxygen species. Thus, the cellular transport of iron must be tightly regulated. In the human b...
Autores principales: | Ito, Hiromu, Kurokawa, Hiromi, Hirayama, Aki, P. Indo, Hiroko, J. Majima, Hideyuki, Matsui, Hirofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703790/ https://www.ncbi.nlm.nih.gov/pubmed/29203959 http://dx.doi.org/10.3164/jcbn.17-8 |
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