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Alpha-helicoidal HEAT-like Repeat Proteins (αRep) Selected as Interactors of HIV-1 Nucleocapsid Negatively Interfere with Viral Genome Packaging and Virus Maturation

A new generation of artificial proteins, derived from alpha-helicoidal HEAT-like repeat protein scaffolds (αRep), was previously characterized as an effective source of intracellular interfering proteins. In this work, a phage-displayed library of αRep was screened on a region of HIV-1 Gag polyprote...

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Detalles Bibliográficos
Autores principales:	Hadpech, Sudarat, Nangola, Sawitree, Chupradit, Koollawat, Fanhchaksai, Kanda, Furnon, Wilhelm, Urvoas, Agathe, Valerio-Lepiniec, Marie, Minard, Philippe, Boulanger, Pierre, Hong, Saw-See, Tayapiwatana, Chatchai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703948/ https://www.ncbi.nlm.nih.gov/pubmed/29180782 http://dx.doi.org/10.1038/s41598-017-16451-w

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