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Post-zygotic genomic changes in glutamate and dopamine pathway genes may explain discordance of monozygotic twins for schizophrenia
BACKGROUND: Monozygotic twins are valuable in assessing the genetic vs environmental contribution to diseases. In the era of complete genome sequences, they allow identification of mutational mechanisms and specific genes and pathways that offer predisposition to the development of complex diseases...
Autores principales: | Castellani, C. A., Melka, M. G., Gui, J. L., Gallo, A. J., O’Reilly, R. L., Singh, S. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704032/ https://www.ncbi.nlm.nih.gov/pubmed/29181591 http://dx.doi.org/10.1186/s40169-017-0174-1 |
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