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Post-zygotic genomic changes in glutamate and dopamine pathway genes may explain discordance of monozygotic twins for schizophrenia

BACKGROUND: Monozygotic twins are valuable in assessing the genetic vs environmental contribution to diseases. In the era of complete genome sequences, they allow identification of mutational mechanisms and specific genes and pathways that offer predisposition to the development of complex diseases...

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Detalles Bibliográficos
Autores principales: Castellani, C. A., Melka, M. G., Gui, J. L., Gallo, A. J., O’Reilly, R. L., Singh, S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704032/
https://www.ncbi.nlm.nih.gov/pubmed/29181591
http://dx.doi.org/10.1186/s40169-017-0174-1

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