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A generalized quantitative antibody homeostasis model: maintenance of global antibody equilibrium by effector functions
The homeostasis of antibodies can be characterized as a balanced production, target-binding and receptor-mediated elimination regulated by an interaction network, which controls B-cell development and selection. Recently, we proposed a quantitative model to describe how the concentration and affinit...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704100/ https://www.ncbi.nlm.nih.gov/pubmed/29201362 http://dx.doi.org/10.1038/cti.2017.50 |