Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report

Autoimmune hemolytic anemia is a rare hematologic entity in children. Etiologies are mainly viruses or bacteria. We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6-month-old infant with acute Cytomegalovirus inf...

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Autores principales: Khalifeh, Hassan K., Mourad, Youmna M., Chamoun, Cynthia T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704128/
https://www.ncbi.nlm.nih.gov/pubmed/29099741
http://dx.doi.org/10.3390/children4110094
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author Khalifeh, Hassan K.
Mourad, Youmna M.
Chamoun, Cynthia T.
author_facet Khalifeh, Hassan K.
Mourad, Youmna M.
Chamoun, Cynthia T.
author_sort Khalifeh, Hassan K.
collection PubMed
description Autoimmune hemolytic anemia is a rare hematologic entity in children. Etiologies are mainly viruses or bacteria. We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6-month-old infant with acute Cytomegalovirus infection that responded well to corticotherapy and intraveneous immunoglobulins without using blood component transfusion. This case demonstrates the importance of recognizing CMV in infantile Autoimmune Hemolytic Anemia, especially because hemolysis can be severe and lethal.
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spelling pubmed-57041282017-11-30 Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report Khalifeh, Hassan K. Mourad, Youmna M. Chamoun, Cynthia T. Children (Basel) Case Report Autoimmune hemolytic anemia is a rare hematologic entity in children. Etiologies are mainly viruses or bacteria. We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6-month-old infant with acute Cytomegalovirus infection that responded well to corticotherapy and intraveneous immunoglobulins without using blood component transfusion. This case demonstrates the importance of recognizing CMV in infantile Autoimmune Hemolytic Anemia, especially because hemolysis can be severe and lethal. MDPI 2017-11-03 /pmc/articles/PMC5704128/ /pubmed/29099741 http://dx.doi.org/10.3390/children4110094 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Khalifeh, Hassan K.
Mourad, Youmna M.
Chamoun, Cynthia T.
Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report
title Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report
title_full Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report
title_fullStr Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report
title_full_unstemmed Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report
title_short Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report
title_sort infantile cytomegalovirus-associated severe warm autoimmune hemolytic anemia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704128/
https://www.ncbi.nlm.nih.gov/pubmed/29099741
http://dx.doi.org/10.3390/children4110094
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AT chamouncynthiat infantilecytomegalovirusassociatedseverewarmautoimmunehemolyticanemiaacasereport

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