Cargando…
Role of LFA-1 and ICAM-1 in Cancer
The lymphocyte function-associated antigen-1 (LFA-1) (also known as CD11a/CD18 and α(L)β(2)), is just one of many integrins in the human body, but its significance is derived from its exclusive presence in leukocytes. In this review, we summarize the studies relating LFA-1 and its major ligand ICAM-...
Autores principales: | Reina, Manuel, Espel, Enric |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704171/ https://www.ncbi.nlm.nih.gov/pubmed/29099772 http://dx.doi.org/10.3390/cancers9110153 |
Ejemplares similares
-
ICAM-3 interacts with LFA-1 and regulates the LFA-1/ICAM-1 cell adhesion pathway
Publicado: (1993) -
Involvement of the "I" domain of LFA-1 in selective binding to ligands ICAM-1 and ICAM-3
Publicado: (1994) -
LFA-1/ICAM-1 Interaction as a Therapeutic Target in Dry Eye Disease
por: Pflugfelder, Stephen C., et al.
Publicado: (2017) -
Probing Single Icam-1/Lfa-1 Interaction under External Force
por: Zhang, Xiaohui, et al.
Publicado: (2002) -
Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1
Publicado: (1991)