Piperidylmethyloxychalcone improves immune-mediated acute liver failure via inhibiting TAK1 activity

Mice deficient in the toll-like receptor (TLR) or the myeloid differentiation factor 88 (MyD88) are resistant to acute liver failure (ALF) with sudden death of hepatocytes. Chalcone derivatives from medicinal plants protect from hepatic damages including ALF, but their mechanisms remain to be clarif...

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Detalles Bibliográficos
Autores principales: Park, Sun Hong, Kwak, Jeong-Ah, Jung, Sang-Hun, Ahn, Byeongwoo, Cho, Won-Jea, Yun, Cheong-Yong, Na, Chang Seon, Hwang, Bang Yeon, Hong, Jin Tae, Han, Sang-Bae, Kim, Youngsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704185/
https://www.ncbi.nlm.nih.gov/pubmed/29147012
http://dx.doi.org/10.1038/emm.2017.156

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