Cargando…

Generation of an osteoblast-based artificial niche that supports in vitro B lymphopoiesis

B lymphocytes are produced from hematopoietic stem cells (HSCs) through the highly ordered process of B lymphopoiesis, which is regulated by a complex network of cytokines, chemokines and cell adhesion molecules derived from the hematopoietic niche. Primary osteoblasts function as an osteoblastic ni...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jiyeon, Choi, Seunga, Kim, Hyeonkyeong, Lee, Nari, Yun, Hyeongseok, Kim, Sumi, Jeong, Seong-Tae, Rho, Jaerang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704192/
https://www.ncbi.nlm.nih.gov/pubmed/29170473
http://dx.doi.org/10.1038/emm.2017.189