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Carbon monoxide prevents TNF-α-induced eNOS downregulation by inhibiting NF-κB-responsive miR-155-5p biogenesis
Heme oxygenase-1-derived carbon monoxide prevents inflammatory vascular disorders. To date, there is no clear evidence that HO-1/CO prevents endothelial dysfunction associated with the downregulation of endothelial NO synthesis in human endothelial cells stimulated with TNF-α. Here, we found that th...
Autores principales: | Choi, Seunghwan, Kim, Joohwan, Kim, Ji-Hee, Lee, Dong-Keon, Park, Wonjin, Park, Minsik, Kim, Suji, Hwang, Jong Yun, Won, Moo-Ho, Choi, Yoon Kyung, Ryoo, Sungwoo, Ha, Kwon-Soo, Kwon, Young-Guen, Kim, Young-Myeong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704195/ https://www.ncbi.nlm.nih.gov/pubmed/29170479 http://dx.doi.org/10.1038/emm.2017.193 |
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