The HMGA1 Pseudogene 7 Induces miR-483 and miR-675 Upregulation by Activating Egr1 through a ceRNA Mechanism

Several studies have established that pseudogene mRNAs can work as competing endogenous RNAs and, when deregulated, play a key role in the onset of human neoplasias. Recently, we have isolated two HMGA1 pseudogenes, HMGA1P6 and HMGA1P7. These pseudogenes have a critical role in cancer progression, a...

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Detalles Bibliográficos
Autores principales: De Martino, Marco, Palma, Giuseppe, Azzariti, Amalia, Arra, Claudio, Fusco, Alfredo, Esposito, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704243/
https://www.ncbi.nlm.nih.gov/pubmed/29149041
http://dx.doi.org/10.3390/genes8110330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704243/
https://www.ncbi.nlm.nih.gov/pubmed/29149041
http://dx.doi.org/10.3390/genes8110330

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