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The HMGA1 Pseudogene 7 Induces miR-483 and miR-675 Upregulation by Activating Egr1 through a ceRNA Mechanism
Several studies have established that pseudogene mRNAs can work as competing endogenous RNAs and, when deregulated, play a key role in the onset of human neoplasias. Recently, we have isolated two HMGA1 pseudogenes, HMGA1P6 and HMGA1P7. These pseudogenes have a critical role in cancer progression, a...
Autores principales: | De Martino, Marco, Palma, Giuseppe, Azzariti, Amalia, Arra, Claudio, Fusco, Alfredo, Esposito, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704243/ https://www.ncbi.nlm.nih.gov/pubmed/29149041 http://dx.doi.org/10.3390/genes8110330 |
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