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Small interfering RNA against ERK1/2 attenuates cigarette smoke-induced pulmonary vascular remodeling

Cigarette smoke may contribute to pulmonary vascular remodeling (PVR), a result of the proliferation of pulmonary artery smooth muscle cells (PASMCs), before pulmonary hypertension in chronic obstructive pulmonary disease (COPD). Activated extracellular signal-regulated kinases 1 and 2 (ERK1/2) are...

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Detalles Bibliográficos
Autores principales: Yu, Muqing, Liu, Xiansheng, Wu, Hongxu, Ni, Wang, Chen, Shixin, Xu, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704260/
https://www.ncbi.nlm.nih.gov/pubmed/29201166
http://dx.doi.org/10.3892/etm.2017.5160

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