Anti-nociceptive effect of dexmedetomidine in a rat model of monoarthritis via suppression of the TLR4/NF-κB p65 pathway

As a therapeutic target for neuropathic pain, the anti-nociceptive effects of α 2-adrenoceptors (α2AR) have attracted attention. Dexmedetomidine (DEX), a potent and highly selective α2AR agonist, has exhibited significant analgesic effects in neuropathic pain, but the underlying mechanism has remain...

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Detalles Bibliográficos
Autores principales: Ji, Dong, Zhou, Yalan, Li, Shuangshuang, Li, Dai, Chen, Hui, Xiong, Yuanchang, Zhang, Yuqiu, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704272/
https://www.ncbi.nlm.nih.gov/pubmed/29201195
http://dx.doi.org/10.3892/etm.2017.5196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704272/
https://www.ncbi.nlm.nih.gov/pubmed/29201195
http://dx.doi.org/10.3892/etm.2017.5196

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