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Anti-nociceptive effect of dexmedetomidine in a rat model of monoarthritis via suppression of the TLR4/NF-κB p65 pathway

As a therapeutic target for neuropathic pain, the anti-nociceptive effects of α 2-adrenoceptors (α2AR) have attracted attention. Dexmedetomidine (DEX), a potent and highly selective α2AR agonist, has exhibited significant analgesic effects in neuropathic pain, but the underlying mechanism has remain...

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Detalles Bibliográficos
Autores principales:	Ji, Dong, Zhou, Yalan, Li, Shuangshuang, Li, Dai, Chen, Hui, Xiong, Yuanchang, Zhang, Yuqiu, Xu, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704272/ https://www.ncbi.nlm.nih.gov/pubmed/29201195 http://dx.doi.org/10.3892/etm.2017.5196

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