Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites

[Image: see text] Biomimicry valuably allows the understanding of the essential chemical components required to recapitulate biological function, yet direct strategies for evaluating the roles of amino acids in proteins can be limited by access to suitable, subtly-altered unnatural variants. Here we...

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Detalles Bibliográficos
Autores principales: Dadová, Jitka, Wu, Kuan-Jung, Isenegger, Patrick G., Errey, James C., Bernardes, Gonçalo J. L., Chalker, Justin M., Raich, Lluís, Rovira, Carme, Davis, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704290/
https://www.ncbi.nlm.nih.gov/pubmed/29202018
http://dx.doi.org/10.1021/acscentsci.7b00341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704290/
https://www.ncbi.nlm.nih.gov/pubmed/29202018
http://dx.doi.org/10.1021/acscentsci.7b00341

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