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Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory
The evidence for the reverse transcriptase mechanism of somatic hypermutation is substantial and multifactorial. In this 60th anniversary year of the publication of Sir MacFarlane Burnet’s Clonal Selection Theory, the evidence is briefly reviewed and updated.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704389/ https://www.ncbi.nlm.nih.gov/pubmed/29218047 http://dx.doi.org/10.3389/fimmu.2017.01611 |
| _version_ | 1783281883903164416 |
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| author | Steele, Edward J. |
| author_facet | Steele, Edward J. |
| author_sort | Steele, Edward J. |
| collection | PubMed |
| description | The evidence for the reverse transcriptase mechanism of somatic hypermutation is substantial and multifactorial. In this 60th anniversary year of the publication of Sir MacFarlane Burnet’s Clonal Selection Theory, the evidence is briefly reviewed and updated. |
| format | Online Article Text |
| id | pubmed-5704389 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Frontiers Media S.A. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-57043892017-12-07 Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory Steele, Edward J. Front Immunol Immunology The evidence for the reverse transcriptase mechanism of somatic hypermutation is substantial and multifactorial. In this 60th anniversary year of the publication of Sir MacFarlane Burnet’s Clonal Selection Theory, the evidence is briefly reviewed and updated. Frontiers Media S.A. 2017-11-23 /pmc/articles/PMC5704389/ /pubmed/29218047 http://dx.doi.org/10.3389/fimmu.2017.01611 Text en Copyright © 2017 Steele. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| spellingShingle | Immunology Steele, Edward J. Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory |
| title | Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory |
| title_full | Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory |
| title_fullStr | Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory |
| title_full_unstemmed | Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory |
| title_short | Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory |
| title_sort | reverse transcriptase mechanism of somatic hypermutation: 60 years of clonal selection theory |
| topic | Immunology |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704389/ https://www.ncbi.nlm.nih.gov/pubmed/29218047 http://dx.doi.org/10.3389/fimmu.2017.01611 |
| work_keys_str_mv | AT steeleedwardj reversetranscriptasemechanismofsomatichypermutation60yearsofclonalselectiontheory |