Methylene Blue Induced Methemoglobinemia with Acute Kidney Injury in a Glucose-6-Phosphate Dehydrogenase-deficient Patient

Our case was treated with methylene blue for symptomatic nitrobenzene poisoning. After which he developed methemoglobinemia with acute kidney injury due to hemolysis and on further testing, he was found to be glucose-6-phosphate dehydrogenase (G6PD) enzyme deficient. Thus, afterward, the patient was...

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Autores principales: Balwani, M. R., Bawankule, C. P., Ramteke, V., Tolani, P., Vakil, S., Yadav, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704414/
https://www.ncbi.nlm.nih.gov/pubmed/29217886
http://dx.doi.org/10.4103/ijn.IJN_316_16
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author Balwani, M. R.
Bawankule, C. P.
Ramteke, V.
Tolani, P.
Vakil, S.
Yadav, R.
author_facet Balwani, M. R.
Bawankule, C. P.
Ramteke, V.
Tolani, P.
Vakil, S.
Yadav, R.
author_sort Balwani, M. R.
collection PubMed
description Our case was treated with methylene blue for symptomatic nitrobenzene poisoning. After which he developed methemoglobinemia with acute kidney injury due to hemolysis and on further testing, he was found to be glucose-6-phosphate dehydrogenase (G6PD) enzyme deficient. Thus, afterward, the patient was treated with only available mode of treatment as repeated blood transfusions and ascorbic acid with dialysis support to which the patient responded. Thus, it is important to evaluate for the G6PD deficiency where methylene blue treatment is planned as an antidote to nitrobenzene compounds poisoning.
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spelling pubmed-57044142017-12-07 Methylene Blue Induced Methemoglobinemia with Acute Kidney Injury in a Glucose-6-Phosphate Dehydrogenase-deficient Patient Balwani, M. R. Bawankule, C. P. Ramteke, V. Tolani, P. Vakil, S. Yadav, R. Indian J Nephrol Case Report Our case was treated with methylene blue for symptomatic nitrobenzene poisoning. After which he developed methemoglobinemia with acute kidney injury due to hemolysis and on further testing, he was found to be glucose-6-phosphate dehydrogenase (G6PD) enzyme deficient. Thus, afterward, the patient was treated with only available mode of treatment as repeated blood transfusions and ascorbic acid with dialysis support to which the patient responded. Thus, it is important to evaluate for the G6PD deficiency where methylene blue treatment is planned as an antidote to nitrobenzene compounds poisoning. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5704414/ /pubmed/29217886 http://dx.doi.org/10.4103/ijn.IJN_316_16 Text en Copyright: © 2017 Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Balwani, M. R.
Bawankule, C. P.
Ramteke, V.
Tolani, P.
Vakil, S.
Yadav, R.
Methylene Blue Induced Methemoglobinemia with Acute Kidney Injury in a Glucose-6-Phosphate Dehydrogenase-deficient Patient
title Methylene Blue Induced Methemoglobinemia with Acute Kidney Injury in a Glucose-6-Phosphate Dehydrogenase-deficient Patient
title_full Methylene Blue Induced Methemoglobinemia with Acute Kidney Injury in a Glucose-6-Phosphate Dehydrogenase-deficient Patient
title_fullStr Methylene Blue Induced Methemoglobinemia with Acute Kidney Injury in a Glucose-6-Phosphate Dehydrogenase-deficient Patient
title_full_unstemmed Methylene Blue Induced Methemoglobinemia with Acute Kidney Injury in a Glucose-6-Phosphate Dehydrogenase-deficient Patient
title_short Methylene Blue Induced Methemoglobinemia with Acute Kidney Injury in a Glucose-6-Phosphate Dehydrogenase-deficient Patient
title_sort methylene blue induced methemoglobinemia with acute kidney injury in a glucose-6-phosphate dehydrogenase-deficient patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704414/
https://www.ncbi.nlm.nih.gov/pubmed/29217886
http://dx.doi.org/10.4103/ijn.IJN_316_16
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