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Epigenetic modifications of the VGF gene in human non-small cell lung cancer tissues pave the way towards enhanced expression
Hwang et al. recently showed that VGF substantially contributes to the resistance of human lung cancer cells towards epidermal growth factor receptor kinase inhibitors. This was further linked to enhanced epithelial–mesenchymal transition. Here, we demonstrate that VGF is epigenetically modified in...
Autores principales: | Marwitz, Sebastian, Heinbockel, Lena, Scheufele, Swetlana, Nitschkowski, Dörte, Kugler, Christian, Perner, Sven, Reck, Martin, Ammerpohl, Ole, Goldmann, Torsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704452/ https://www.ncbi.nlm.nih.gov/pubmed/29209432 http://dx.doi.org/10.1186/s13148-017-0423-6 |
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