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A unique cysteine-rich zinc finger domain present in a majority of class II ribonucleotide reductases mediates catalytic turnover

Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to the corresponding deoxyribonucleotides, used in DNA synthesis and repair. Two different mechanisms help deliver the required electrons to the RNR active site. Formate can be used as reductant directly in the active site, o...

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Detalles Bibliográficos
Autores principales:	Loderer, Christoph, Jonna, Venkateswara Rao, Crona, Mikael, Rozman Grinberg, Inna, Sahlin, Margareta, Hofer, Anders, Lundin, Daniel, Sjöberg, Britt-Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704485/ https://www.ncbi.nlm.nih.gov/pubmed/28972190 http://dx.doi.org/10.1074/jbc.M117.806331

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