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Combining cytogenetic and epigenetic approaches in chronic lymphocytic leukemia improves prognosis prediction for patients with isolated 13q deletion

BACKGROUND: Both defective DNA methylation and active DNA demethylation processes are emerging as important risk factors in chronic lymphocytic leukemia (CLL). However, associations between 5-cytosine epigenetic markers and the most frequent chromosomal abnormalities detected in CLL remain to be est...

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Detalles Bibliográficos
Autores principales:	Bagacean, Cristina, Le Dantec, Christelle, Berthou, Christian, Tempescul, Adrian, Saad, Hussam, Bordron, Anne, Zdrenghea, Mihnea, Cristea, Victor, Douet-Guilbert, Nathalie, Renaudineau, Yves
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704505/ https://www.ncbi.nlm.nih.gov/pubmed/29209431 http://dx.doi.org/10.1186/s13148-017-0422-7

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