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Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka

OBJECTIVE: Although medical expulsive therapy (MET) is shown to be effective for ureteric calculi, the optimum duration and the stone size suitable for MET are not well established yet. The objectives of the study were to determine the optimum duration and maximum stone size suitable for MET. RESULT...

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Autores principales: Jayawardene, Malaka Dharmakeerthi, Balagobi, Balasingam, Ambegoda, A. L. A. M. C., Vidanapathirana, Sanjeewa, Wijayagunawardane, G. W. A. S. K., Senthan, V., Ranasinghe, D. D., Abeygunasekera, Anuruddha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704535/
https://www.ncbi.nlm.nih.gov/pubmed/29183356
http://dx.doi.org/10.1186/s13104-017-2974-1
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author Jayawardene, Malaka Dharmakeerthi
Balagobi, Balasingam
Ambegoda, A. L. A. M. C.
Vidanapathirana, Sanjeewa
Wijayagunawardane, G. W. A. S. K.
Senthan, V.
Ranasinghe, D. D.
Abeygunasekera, Anuruddha M.
author_facet Jayawardene, Malaka Dharmakeerthi
Balagobi, Balasingam
Ambegoda, A. L. A. M. C.
Vidanapathirana, Sanjeewa
Wijayagunawardane, G. W. A. S. K.
Senthan, V.
Ranasinghe, D. D.
Abeygunasekera, Anuruddha M.
author_sort Jayawardene, Malaka Dharmakeerthi
collection PubMed
description OBJECTIVE: Although medical expulsive therapy (MET) is shown to be effective for ureteric calculi, the optimum duration and the stone size suitable for MET are not well established yet. The objectives of the study were to determine the optimum duration and maximum stone size suitable for MET. RESULTS: All patients with radiologically confirmed uncomplicated ureteric calculi treated with MET using tamsulosin over a period of 6 months in the outpatient setting were followed up. There were 213 patients. 165 were men. Mean age was 42 years. At presentation 42 stones were in upper ureter (19.7%), 51 in mid ureter (23.9%), 120 in lower ureter (56.3%). The majority (82.7%) of stones were less than 10 mm. Seven stones (3.3%) were over 15 mm. Ninety-two (43.2%) patients had spontaneous passage of stones within 6-weeks of MET. Another 38.9% passed the stone within the next 6-weeks. Thirty-eight patients (17.8%) required surgery. Uncomplicated ureteric stones up to 10 mm can be given a trial of MET using tamsulosin which can be extended up to 12-weeks with a success rate over 92%. This may have substantial clinical and fiscal benefits by reducing the number of interventional procedures especially in resource-poor settings. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-017-2974-1) contains supplementary material, which is available to authorized users.
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spelling pubmed-57045352017-12-05 Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka Jayawardene, Malaka Dharmakeerthi Balagobi, Balasingam Ambegoda, A. L. A. M. C. Vidanapathirana, Sanjeewa Wijayagunawardane, G. W. A. S. K. Senthan, V. Ranasinghe, D. D. Abeygunasekera, Anuruddha M. BMC Res Notes Research Note OBJECTIVE: Although medical expulsive therapy (MET) is shown to be effective for ureteric calculi, the optimum duration and the stone size suitable for MET are not well established yet. The objectives of the study were to determine the optimum duration and maximum stone size suitable for MET. RESULTS: All patients with radiologically confirmed uncomplicated ureteric calculi treated with MET using tamsulosin over a period of 6 months in the outpatient setting were followed up. There were 213 patients. 165 were men. Mean age was 42 years. At presentation 42 stones were in upper ureter (19.7%), 51 in mid ureter (23.9%), 120 in lower ureter (56.3%). The majority (82.7%) of stones were less than 10 mm. Seven stones (3.3%) were over 15 mm. Ninety-two (43.2%) patients had spontaneous passage of stones within 6-weeks of MET. Another 38.9% passed the stone within the next 6-weeks. Thirty-eight patients (17.8%) required surgery. Uncomplicated ureteric stones up to 10 mm can be given a trial of MET using tamsulosin which can be extended up to 12-weeks with a success rate over 92%. This may have substantial clinical and fiscal benefits by reducing the number of interventional procedures especially in resource-poor settings. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-017-2974-1) contains supplementary material, which is available to authorized users. BioMed Central 2017-11-28 /pmc/articles/PMC5704535/ /pubmed/29183356 http://dx.doi.org/10.1186/s13104-017-2974-1 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Jayawardene, Malaka Dharmakeerthi
Balagobi, Balasingam
Ambegoda, A. L. A. M. C.
Vidanapathirana, Sanjeewa
Wijayagunawardane, G. W. A. S. K.
Senthan, V.
Ranasinghe, D. D.
Abeygunasekera, Anuruddha M.
Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka
title Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka
title_full Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka
title_fullStr Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka
title_full_unstemmed Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka
title_short Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka
title_sort outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in sri lanka
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704535/
https://www.ncbi.nlm.nih.gov/pubmed/29183356
http://dx.doi.org/10.1186/s13104-017-2974-1
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