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HLA genotyping by next-generation sequencing of complementary DNA

BACKGROUND: Genotyping of the human leucocyte antigen (HLA) is indispensable for various medical treatments. However, unambiguous genotyping is technically challenging due to high polymorphism of the corresponding genomic region. Next-generation sequencing is changing the landscape of genotyping. In...

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Detalles Bibliográficos
Autores principales:	Segawa, Hidenobu, Kukita, Yoji, Kato, Kikuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704545/ https://www.ncbi.nlm.nih.gov/pubmed/29179676 http://dx.doi.org/10.1186/s12864-017-4300-7

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