Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report

BACKGROUND: Hepatobiliary tuberculosis includes miliary, tuberculous hepatitis or localized forms. The localised form is extremely uncommon and can mimic malignancy. Still rarer is its presentation as sclerosing cholangitis. CASE PRESENTATION: A 50 year male presented with acute onset jaundice, sign...

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Autores principales: Jain, Aleena, Chaturvedi, Rachana, Kantharia, Chetan, Joshi, Amita, Londhe, Mangesh, Kekan, Mayura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704558/
https://www.ncbi.nlm.nih.gov/pubmed/29179696
http://dx.doi.org/10.1186/s12876-017-0690-x
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author Jain, Aleena
Chaturvedi, Rachana
Kantharia, Chetan
Joshi, Amita
Londhe, Mangesh
Kekan, Mayura
author_facet Jain, Aleena
Chaturvedi, Rachana
Kantharia, Chetan
Joshi, Amita
Londhe, Mangesh
Kekan, Mayura
author_sort Jain, Aleena
collection PubMed
description BACKGROUND: Hepatobiliary tuberculosis includes miliary, tuberculous hepatitis or localized forms. The localised form is extremely uncommon and can mimic malignancy. Still rarer is its presentation as sclerosing cholangitis. CASE PRESENTATION: A 50 year male presented with acute onset jaundice, significant weight loss and elevated liver enzymes with clinico-radiological suspicion of cholangiocarcinoma. A left hepatectomy was done and dilated bile ducts filled with caseous necrotic material were seen intra-operatively. Histopathology suggested localized hepatobiliary tuberculosis with features of secondary sclerosing cholangitis. CONCLUSION: Localised hepatobiliary tuberculosis can cause diagnostic difficulties and its possibility should be considered especially in endemic areas.
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spelling pubmed-57045582017-12-05 Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report Jain, Aleena Chaturvedi, Rachana Kantharia, Chetan Joshi, Amita Londhe, Mangesh Kekan, Mayura BMC Gastroenterol Case Report BACKGROUND: Hepatobiliary tuberculosis includes miliary, tuberculous hepatitis or localized forms. The localised form is extremely uncommon and can mimic malignancy. Still rarer is its presentation as sclerosing cholangitis. CASE PRESENTATION: A 50 year male presented with acute onset jaundice, significant weight loss and elevated liver enzymes with clinico-radiological suspicion of cholangiocarcinoma. A left hepatectomy was done and dilated bile ducts filled with caseous necrotic material were seen intra-operatively. Histopathology suggested localized hepatobiliary tuberculosis with features of secondary sclerosing cholangitis. CONCLUSION: Localised hepatobiliary tuberculosis can cause diagnostic difficulties and its possibility should be considered especially in endemic areas. BioMed Central 2017-11-28 /pmc/articles/PMC5704558/ /pubmed/29179696 http://dx.doi.org/10.1186/s12876-017-0690-x Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Jain, Aleena
Chaturvedi, Rachana
Kantharia, Chetan
Joshi, Amita
Londhe, Mangesh
Kekan, Mayura
Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report
title Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report
title_full Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report
title_fullStr Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report
title_full_unstemmed Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report
title_short Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report
title_sort secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704558/
https://www.ncbi.nlm.nih.gov/pubmed/29179696
http://dx.doi.org/10.1186/s12876-017-0690-x
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