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Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population
OBJECTIVE: To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. RESULTS: Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational di...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704589/ https://www.ncbi.nlm.nih.gov/pubmed/29179745 http://dx.doi.org/10.1186/s13104-017-2944-7 |
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author | Munang, Yvonne Nangeh Noubiap, Jean Jacques Danwang, Celestin Sama, Julius Dohbit Azabji-Kenfack, Marcel Mbanya, Jean Claude Sobngwi, Eugene |
author_facet | Munang, Yvonne Nangeh Noubiap, Jean Jacques Danwang, Celestin Sama, Julius Dohbit Azabji-Kenfack, Marcel Mbanya, Jean Claude Sobngwi, Eugene |
author_sort | Munang, Yvonne Nangeh |
collection | PubMed |
description | OBJECTIVE: To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. RESULTS: Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic’s 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-017-2944-7) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5704589 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-57045892017-12-05 Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population Munang, Yvonne Nangeh Noubiap, Jean Jacques Danwang, Celestin Sama, Julius Dohbit Azabji-Kenfack, Marcel Mbanya, Jean Claude Sobngwi, Eugene BMC Res Notes Research Note OBJECTIVE: To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. RESULTS: Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic’s 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-017-2944-7) contains supplementary material, which is available to authorized users. BioMed Central 2017-11-28 /pmc/articles/PMC5704589/ /pubmed/29179745 http://dx.doi.org/10.1186/s13104-017-2944-7 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Note Munang, Yvonne Nangeh Noubiap, Jean Jacques Danwang, Celestin Sama, Julius Dohbit Azabji-Kenfack, Marcel Mbanya, Jean Claude Sobngwi, Eugene Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
title | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
title_full | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
title_fullStr | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
title_full_unstemmed | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
title_short | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
title_sort | reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-saharan african population |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704589/ https://www.ncbi.nlm.nih.gov/pubmed/29179745 http://dx.doi.org/10.1186/s13104-017-2944-7 |
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