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Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study

BACKGROUND: The frequency of primary cardiac tumors is rare at about 0.3% by autopsy. Our objective was to investigate the characteristics and locations of cardiac tumors and to provide a prognostic analysis in our hospital. METHODS: We collected data on 95 patients with echocardiographic diagnosis...

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Autores principales: Nomoto, Natsumi, Tani, Tomoko, Konda, Toshiko, Kim, Kitae, Kitai, Takeshi, Ota, Mitsuhiko, Kaji, Shuichiro, Imai, Yukihiro, Okada, Yukikatsu, Furukawa, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704631/
https://www.ncbi.nlm.nih.gov/pubmed/29183343
http://dx.doi.org/10.1186/s13019-017-0672-7
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author Nomoto, Natsumi
Tani, Tomoko
Konda, Toshiko
Kim, Kitae
Kitai, Takeshi
Ota, Mitsuhiko
Kaji, Shuichiro
Imai, Yukihiro
Okada, Yukikatsu
Furukawa, Yutaka
author_facet Nomoto, Natsumi
Tani, Tomoko
Konda, Toshiko
Kim, Kitae
Kitai, Takeshi
Ota, Mitsuhiko
Kaji, Shuichiro
Imai, Yukihiro
Okada, Yukikatsu
Furukawa, Yutaka
author_sort Nomoto, Natsumi
collection PubMed
description BACKGROUND: The frequency of primary cardiac tumors is rare at about 0.3% by autopsy. Our objective was to investigate the characteristics and locations of cardiac tumors and to provide a prognostic analysis in our hospital. METHODS: We collected data on 95 patients with echocardiographic diagnosis or detection of cardiac tumors in a prospective analysis from 1999 to 2014. The median follow-up period was 43 months (0.5–183 months). RESULTS: The subjects included 56 men and 39 women with a mean age of 65 years. Clinical diagnosis revealed primary tumors in 61 patients (64%) and secondary metastatic tumors in 34 patients (36%). In the 61 patients, 41 patients (67%) underwent surgery and tissue samples were obtained. Of these 41 patients, benign tumors were found in 30 cases (73%). One patient (2%) was diagnosed with thrombus. Among the benign tumors, myxoma (67%) was the most common type followed by papillary fibroelastoma (23%). The most common site was the left atrium (35%) followed by the right atrium (25%). Primary malignant tumors were diagnosed in 10 cases (24%), including 6 angiosarcomas, 3 lymphomas, and 1 leiomyosarcoma. The diagnostic accuracy of echocardiography was 80%. The patients with benign tumors were all alive at the end of the follow-up period. In contrast, 7 patients with malignant tumors died (70%) (p < 0.0001). CONCLUSIONS: Our data is in line with previous literature. Our study also suggests the necessity of extending our knowledge of the characteristics of cardiac tumors for diagnosis.
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spelling pubmed-57046312017-12-05 Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study Nomoto, Natsumi Tani, Tomoko Konda, Toshiko Kim, Kitae Kitai, Takeshi Ota, Mitsuhiko Kaji, Shuichiro Imai, Yukihiro Okada, Yukikatsu Furukawa, Yutaka J Cardiothorac Surg Research Article BACKGROUND: The frequency of primary cardiac tumors is rare at about 0.3% by autopsy. Our objective was to investigate the characteristics and locations of cardiac tumors and to provide a prognostic analysis in our hospital. METHODS: We collected data on 95 patients with echocardiographic diagnosis or detection of cardiac tumors in a prospective analysis from 1999 to 2014. The median follow-up period was 43 months (0.5–183 months). RESULTS: The subjects included 56 men and 39 women with a mean age of 65 years. Clinical diagnosis revealed primary tumors in 61 patients (64%) and secondary metastatic tumors in 34 patients (36%). In the 61 patients, 41 patients (67%) underwent surgery and tissue samples were obtained. Of these 41 patients, benign tumors were found in 30 cases (73%). One patient (2%) was diagnosed with thrombus. Among the benign tumors, myxoma (67%) was the most common type followed by papillary fibroelastoma (23%). The most common site was the left atrium (35%) followed by the right atrium (25%). Primary malignant tumors were diagnosed in 10 cases (24%), including 6 angiosarcomas, 3 lymphomas, and 1 leiomyosarcoma. The diagnostic accuracy of echocardiography was 80%. The patients with benign tumors were all alive at the end of the follow-up period. In contrast, 7 patients with malignant tumors died (70%) (p < 0.0001). CONCLUSIONS: Our data is in line with previous literature. Our study also suggests the necessity of extending our knowledge of the characteristics of cardiac tumors for diagnosis. BioMed Central 2017-11-28 /pmc/articles/PMC5704631/ /pubmed/29183343 http://dx.doi.org/10.1186/s13019-017-0672-7 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Nomoto, Natsumi
Tani, Tomoko
Konda, Toshiko
Kim, Kitae
Kitai, Takeshi
Ota, Mitsuhiko
Kaji, Shuichiro
Imai, Yukihiro
Okada, Yukikatsu
Furukawa, Yutaka
Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study
title Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study
title_full Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study
title_fullStr Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study
title_full_unstemmed Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study
title_short Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study
title_sort primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704631/
https://www.ncbi.nlm.nih.gov/pubmed/29183343
http://dx.doi.org/10.1186/s13019-017-0672-7
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