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Sulfation and amidinohydrolysis in the biosynthesis of giant linear polyenes

Clethramycin from Streptomyces malaysiensis DSM4137, and mediomycins (produced together with clethramycin from Streptomyces mediocidicus), are near-identical giant linear polyenes apparently constructed from, respectively, a 4-guanidinobutanoate or 4-aminobutanoate starter unit and 27 polyketide ext...

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Detalles Bibliográficos
Autores principales: Hong, Hui, Samborskyy, Markiyan, Usachova, Katsiaryna, Schnatz, Katharina, Leadlay, Peter F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704753/
https://www.ncbi.nlm.nih.gov/pubmed/29234468
http://dx.doi.org/10.3762/bjoc.13.238

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