Cargando…
Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report
RATIONALE: Asympotamic syringomyelia accompanied with metastatic cerebellar and thoracic spinal intramedullary lymphoma is rare in clinical practice. If the intramedullary lymphoma is large enough, the patient will rapidly develop neurologic signs of spinal injury. The prognosis of this type of comp...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704820/ https://www.ncbi.nlm.nih.gov/pubmed/29145275 http://dx.doi.org/10.1097/MD.0000000000008593 |
_version_ | 1783281976963235840 |
---|---|
author | Zhou, Jia-Jia Xu, Jin-Feng Zheng, Xu-Ning Peng, Guo-Ping |
author_facet | Zhou, Jia-Jia Xu, Jin-Feng Zheng, Xu-Ning Peng, Guo-Ping |
author_sort | Zhou, Jia-Jia |
collection | PubMed |
description | RATIONALE: Asympotamic syringomyelia accompanied with metastatic cerebellar and thoracic spinal intramedullary lymphoma is rare in clinical practice. If the intramedullary lymphoma is large enough, the patient will rapidly develop neurologic signs of spinal injury. The prognosis of this type of complication is always bad. PATIENT CONCERNS: Rapid and correct diagnosis and treatment is important for metastatic extranodal lymphoma with B cell of origin. DIAGNOSES: Syringomyelia accompanied with metastatic cerebellar and thoracic spinal intramedullary lymphoma. INTERVENTIONS: The patient was treated with a combination of systemic chemotherapy and focal radiotherapy and intrathecal therapy. OUTCOMES: Resolution of metastatic lymphoma was not continued after conservative medical management and the patient died finally due to multiple organ failure. LESSONS: Syringomyelia can develop due to the metastatic thoracic intramedullary lymphoma in patients with diffuse malignant large B cell lymphoma. Early and accurate diagnosis, anti-lymphoma treatment, and timely neurosurgical intervention may delay the development of the disease. |
format | Online Article Text |
id | pubmed-5704820 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-57048202017-12-07 Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report Zhou, Jia-Jia Xu, Jin-Feng Zheng, Xu-Ning Peng, Guo-Ping Medicine (Baltimore) 5300 RATIONALE: Asympotamic syringomyelia accompanied with metastatic cerebellar and thoracic spinal intramedullary lymphoma is rare in clinical practice. If the intramedullary lymphoma is large enough, the patient will rapidly develop neurologic signs of spinal injury. The prognosis of this type of complication is always bad. PATIENT CONCERNS: Rapid and correct diagnosis and treatment is important for metastatic extranodal lymphoma with B cell of origin. DIAGNOSES: Syringomyelia accompanied with metastatic cerebellar and thoracic spinal intramedullary lymphoma. INTERVENTIONS: The patient was treated with a combination of systemic chemotherapy and focal radiotherapy and intrathecal therapy. OUTCOMES: Resolution of metastatic lymphoma was not continued after conservative medical management and the patient died finally due to multiple organ failure. LESSONS: Syringomyelia can develop due to the metastatic thoracic intramedullary lymphoma in patients with diffuse malignant large B cell lymphoma. Early and accurate diagnosis, anti-lymphoma treatment, and timely neurosurgical intervention may delay the development of the disease. Wolters Kluwer Health 2017-11-17 /pmc/articles/PMC5704820/ /pubmed/29145275 http://dx.doi.org/10.1097/MD.0000000000008593 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 5300 Zhou, Jia-Jia Xu, Jin-Feng Zheng, Xu-Ning Peng, Guo-Ping Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report |
title | Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report |
title_full | Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report |
title_fullStr | Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report |
title_full_unstemmed | Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report |
title_short | Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report |
title_sort | asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: a case report |
topic | 5300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704820/ https://www.ncbi.nlm.nih.gov/pubmed/29145275 http://dx.doi.org/10.1097/MD.0000000000008593 |
work_keys_str_mv | AT zhoujiajia asymptomaticsyringomyeliaaccompaniedwithmetastaticcerebellarandspinalintramedullarylymphomaacasereport AT xujinfeng asymptomaticsyringomyeliaaccompaniedwithmetastaticcerebellarandspinalintramedullarylymphomaacasereport AT zhengxuning asymptomaticsyringomyeliaaccompaniedwithmetastaticcerebellarandspinalintramedullarylymphomaacasereport AT pengguoping asymptomaticsyringomyeliaaccompaniedwithmetastaticcerebellarandspinalintramedullarylymphomaacasereport |