Combination Analgesic Development for Enhanced Clinical Efficacy (CADENCE Trial): Study Protocol for a Double-Blind, Randomized, Placebo-Controlled Crossover Trial of an Alpha-Lipoic Acid – Pregabalin Combination for the Treatment of Fibromyalgia Pain

BACKGROUND: Fibromyalgia is a clinical disorder commonly presenting with chronic widespread pain as well as sleep disturbance, fatigue, depression, and cognitive dysfunction. There is an urgent need for treatment strategies that provide better pain relief and fewer adverse effects (AEs). Efforts to...

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Detalles Bibliográficos
Autores principales: Gilron, Ian, Tu, Dongsheng, Holden, Ronald, Towheed, Tanveer, Vandenkerkhof, Elizabeth, Milev, Roumen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2017
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705061/
https://www.ncbi.nlm.nih.gov/pubmed/28778847
http://dx.doi.org/10.2196/resprot.8001

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