Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid

While all 2-methylene-19-nor analogs of 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)) tested produce an increase in epidermal thickness in the rhino mouse, only a subset reduce utricle size (comedolysis). All-trans retinoic acid (atRA) also causes epidermal thickening and a reduction in utricle siz...

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Detalles Bibliográficos
Autores principales: Ahrens, Jamie M., Jones, James D., Nieves, Nirca J., Mitzey, Ann M., DeLuca, Hector F., Clagett-Dame, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705097/
https://www.ncbi.nlm.nih.gov/pubmed/29182680
http://dx.doi.org/10.1371/journal.pone.0188887

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