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Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers

Lipid nanoparticles (LNPs) or liposomes are the most widely used drug carriers for nanomedicines. The size of LNPs is one of the essential factors affecting drug delivery efficiency and therapeutic efficiency. Here, we demonstrated the effect of lipid concentration and mixing performance on the LNP...

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Detalles Bibliográficos
Autores principales:	Maeki, Masatoshi, Fujishima, Yuka, Sato, Yusuke, Yasui, Takao, Kaji, Noritada, Ishida, Akihiko, Tani, Hirofumi, Baba, Yoshinobu, Harashima, Hideyoshi, Tokeshi, Manabu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705116/ https://www.ncbi.nlm.nih.gov/pubmed/29182626 http://dx.doi.org/10.1371/journal.pone.0187962

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