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NKT cells contribute to basal IL-4 production but are not required to induce experimental asthma

CD1d-deficiency results in a selective deletion of NKT cells in mice that is reported to prevent murine allergic airway disease (AAD). Because we find 2–3 fold lower basal IL-4 production in CD1d(-) mice than in wild-type (WT) mice, we hypothesized that the contribution made by NKT cells to AAD woul...

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Detalles Bibliográficos
Autores principales:	McKnight, Christopher G., Morris, Suzanne C., Perkins, Charles, Zhu, Zhenqi, Hildeman, David A., Bendelac, Albert, Finkelman, Fred D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705134/ https://www.ncbi.nlm.nih.gov/pubmed/29182669 http://dx.doi.org/10.1371/journal.pone.0188221

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