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HLA and non-HLA genes and familial predisposition to autoimmune diseases in families with a child affected by type 1 diabetes

Genetic predisposition could be assumed to be causing clustering of autoimmunity in individuals and families. We tested whether HLA and non-HLA loci associate with such clustering of autoimmunity. We included 1,745 children with type 1 diabetes from the Finnish Pediatric Diabetes Register. Data on p...

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Detalles Bibliográficos
Autores principales: Parkkola, Anna, Laine, Antti-Pekka, Karhunen, Markku, Härkönen, Taina, Ryhänen, Samppa J., Ilonen, Jorma, Knip, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705143/
https://www.ncbi.nlm.nih.gov/pubmed/29182645
http://dx.doi.org/10.1371/journal.pone.0188402

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