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Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm

Homologous Recombination (HR) repair is essential for repairing DNA double strand breaks (DSB) in dividing cells and preventing tumorigenesis. BRCA2 plays an important role in HR by recruiting the DNA recombinase RAD51 to the DSB. Despite being a popular model organism in genetic and cancer research...

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Detalles Bibliográficos
Autores principales:	Vierstraete, Jeroen, Willaert, Andy, Vermassen, Petra, Coucke, Paul J., Vral, Anne, Claes, Kathleen B. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705637/ https://www.ncbi.nlm.nih.gov/pubmed/29184099 http://dx.doi.org/10.1038/s41598-017-16725-3

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