Cargando…

Adrenomedullin protects Leydig cells against lipopolysaccharide-induced oxidative stress and inflammatory reaction via MAPK/NF-κB signalling pathways

This study aimed to explore the possible benefits of adrenomedullin (ADM) in preventing oxidative stress and inflammation by using an in vitro primary culture model of rat Leydig cells exposed to lipopolysaccharide (LPS). Cell proliferation was detected through CCK-8 and BrdU incorporation assays. R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Wei, Shi, Lei, Li, Ming-yong, Zhou, Pang-hu, Qiu, Bo, Yin, Ke, Zhang, Hui-hui, Gao, Yong, Kang, Ran, Qin, Song-lin, Ning, Jin-zhuo, Wang, Wei, Zhang, Li-jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705677/ https://www.ncbi.nlm.nih.gov/pubmed/29184072 http://dx.doi.org/10.1038/s41598-017-16008-x

Ejemplares similares

Protective Effect of Adrenomedullin on Rat Leydig Cells from Lipopolysaccharide-Induced Inflammation and Apoptosis via the PI3K/Akt Signaling Pathway ADM on Rat Leydig Cells from Inflammation and Apoptosis
por: Zhou, Pang-Hu, et al.
Publicado: (2016)

Adrenomedullin alleviates the pyroptosis of Leydig cells by promoting autophagy via the ROS–AMPK–mTOR axis
por: Li, Ming-yong, et al.
Publicado: (2019)

4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression
por: Chang, Chien-Hsin, et al.
Publicado: (2018)

Ubiquitin-specific protease 8 ameliorates lipopolysaccharide-induced spleen injury via suppression of NF-κB and MAPK signaling pathways
por: Bi, Wei, et al.
Publicado: (2022)

Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways
por: Zhang, Guo-Yu, et al.
Publicado: (2018)

Prognostic Value of Adrenomedullin and Natriuretic Peptides in Uroseptic Patients Induced by Ureteroscopy
por: Hu, Wei, et al.
Publicado: (2016)

The Anti-Inflammatory Mechanism of Flaxseed Linusorbs on Lipopolysaccharide-Induced RAW 264.7 Macrophages by Modulating TLR4/NF-κB/MAPK Pathway
por: Li, Jialong, et al.
Publicado: (2023)

Tanreqing Injection Attenuates Lipopolysaccharide-Induced Airway Inflammation through MAPK/NF-κB Signaling Pathways in Rats Model
por: Liu, Wei, et al.
Publicado: (2016)

Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway
por: Guo, Yujie, et al.
Publicado: (2023)

Enhanced Anti-Inflammatory Effects of Silibinin and Capsaicin Combination in Lipopolysaccharide-Induced RAW264.7 Cells by Inhibiting NF-κB and MAPK Activation
por: Zheng, Yingying, et al.
Publicado: (2022)

Remifentanil Protects against Lipopolysaccharide-Induced Inflammation through PARP-1/NF-κB Signaling Pathway
por: Zhang, Jian-ning, et al.
Publicado: (2019)

Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade
por: Wang, Guangxi, et al.
Publicado: (2017)

Coixol Suppresses NF-κB, MAPK Pathways and NLRP3 Inflammasome Activation in Lipopolysaccharide-Induced RAW 264.7 Cells
por: Hu, Yusheng, et al.
Publicado: (2020)

Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB
por: Huang, Xia, et al.
Publicado: (2017)

Roscovitine protects murine Leydig cells from lipopolysaccharide-induced inflammation
por: Xie, Tiancheng, et al.
Publicado: (2017)

Lipopolysaccharide induces acute bursal atrophy in broiler chicks by activating TLR4-MAPK-NF-κB/AP-1 signaling
por: Ansari, Abdur Rahman, et al.
Publicado: (2017)

Eucalyptus essential oils inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through reducing MAPK and NF-κB pathways
por: Ho, Chen-Lung, et al.
Publicado: (2020)

Dehydromiltirone inhibits osteoclast differentiation in RAW264.7 and bone marrow macrophages by modulating MAPK and NF-κB activity
por: Deng, Wei, et al.
Publicado: (2022)

Antineuroinflammatory Effects of 7,3’,4’-Trihydroxyisoflavone in Lipopolysaccharide-Stimulated BV2 Microglial Cells through MAPK and NF-κB Signaling Suppression
por: Kim, Seon-Kyung, et al.
Publicado: (2021)

Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by targeting the ERK/MAPK pathway
por: Gao, Yongqian, et al.
Publicado: (2016)

Carboxyamidotriazole exerts anti-inflammatory activity in lipopolysaccharide-induced RAW264.7 macrophages by inhibiting NF-κB and MAPKs pathways
por: Lu, Shan, et al.
Publicado: (2020)

Magnoflorine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Suppressing NF-κB and MAPK Activation
por: Guo, Shuai, et al.
Publicado: (2018)

Anti-Inflammatory Effect of Mangostenone F in Lipopolysaccharide-Stimulated RAW264.7 Macrophages by Suppressing NF-κB and MAPK Activation
por: Cho, Byoung Ok, et al.
Publicado: (2014)

Adiporedoxin suppresses endothelial activation via inhibiting MAPK and NF-κB signaling
por: He, Hui, et al.
Publicado: (2016)

Rosmarinic Acid Attenuates the Lipopolysaccharide-Provoked Inflammatory Response of Vascular Smooth Muscle Cell via Inhibition of MAPK/NF-κB Cascade
por: Chen, Ching-Pei, et al.
Publicado: (2022)

Anhuienoside C Ameliorates Collagen-Induced Arthritis through Inhibition of MAPK and NF-κB Signaling Pathways
por: Liu, Qing, et al.
Publicado: (2017)

Dusuqing granules (DSQ) suppress inflammation in Klebsiella pneumonia rat via NF-κB/MAPK signaling
por: Mei, Xue, et al.
Publicado: (2017)

Effect of bacterial endotoxin lipopolysaccharide treatment on duck Leydig cells
por: Lao, Yongcong, et al.
Publicado: (2019)

HMGB1 Acts in Synergy with Lipopolysaccharide in Activating Rheumatoid Synovial Fibroblasts via p38 MAPK and NF-κB Signaling Pathways
por: He, Zheng-Wen, et al.
Publicado: (2013)

5-Hydroxymethylfurfural Mitigates Lipopolysaccharide-Stimulated Inflammation via Suppression of MAPK, NF-κB and mTOR Activation in RAW 264.7 Cells
por: Kong, Fanhui, et al.
Publicado: (2019)

Inhibition of lipopolysaccharide-induced microglia activation by calcitonin gene related peptide and adrenomedullin
por: Consonni, Alessandra, et al.
Publicado: (2011)

Artemisinin Protects Porcine Mammary Epithelial Cells against Lipopolysaccharide-Induced Inflammatory Injury by Regulating the NF-κB and MAPK Signaling Pathways
por: Zhang, Wenfei, et al.
Publicado: (2021)

Anti-inflammatory effects of progesterone through NF-κB and MAPK pathway in lipopolysaccharide- or Escherichia coli-stimulated bovine endometrial stromal cells
por: Cui, Luying, et al.
Publicado: (2022)

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways
por: Peng, Shuang, et al.
Publicado: (2016)

Deacylcynaropicrin Inhibits RANKL-Induced Osteoclastogenesis by Inhibiting NF-κB and MAPK and Promoting M2 Polarization of Macrophages
por: Li, Zhikun, et al.
Publicado: (2019)

Down-regulation of protease-activated receptor 2 ameliorated osteoarthritis in rats through regulation of MAPK/NF-κB signaling pathway in vivo and in vitro
por: Yan, Shichang, et al.
Publicado: (2020)

Mechanism of nuclear factor of activated T-cells mediated FasL expression in corticosterone -treated mouse Leydig tumor cells
por: Chai, Wei-Ran, et al.
Publicado: (2008)

Research on the Mechanism of HMGB1 Regulating Autoimmune Encephalomyelitis by Regulating NF-κB
por: Liu, Lijuan, et al.
Publicado: (2022)

TLR4 Overexpression Aggravates Bacterial Lipopolysaccharide-Induced Apoptosis via Excessive Autophagy and NF-κB/MAPK Signaling in Transgenic Mammal Models
por: Wang, Sutian, et al.
Publicado: (2023)

Brilliant blue G attenuates neuro-inflammation via regulating MAPKs and NF-κB signaling pathways in lipopolysaccharide-induced BV2 microglia cells
por: Wang, Wei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k20h1ro50ip8flopip6t216k9g