Preventive Trichuris suis ova (TSO) treatment protects immunocompetent rabbits from DSS colitis but may be detrimental under conditions of immunosuppression

Trichuris suis ova (TSO) have been tested for therapeutic application in inflammatory bowel diseases (IBD) yet understanding of the underlying mechanisms and safety in an immunocompromised host is limited due to lack of a suitable animal model. We used a recently established rabbit model of dextran...

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Detalles Bibliográficos
Autores principales: Leonardi, Irina, Gerstgrasser, Alexandra, Schmidt, Thomas S. B., Nicholls, Flora, Tewes, Bernhard, Greinwald, Roland, von Mering, Christian, Rogler, Gerhard, Frey-Wagner, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705695/
https://www.ncbi.nlm.nih.gov/pubmed/29184071
http://dx.doi.org/10.1038/s41598-017-16287-4

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