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Notch transactivates Rheb to maintain the multipotency of TSC-null cells

Differentiation abnormalities are a hallmark of tuberous sclerosis complex (TSC) manifestations; however, the genesis of these abnormalities remains unclear. Here we report on mechanisms controlling the multi-lineage, early neuronal progenitor and neural stem-like cell characteristics of lymphangiol...

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Detalles Bibliográficos
Autores principales:	Cho, Jun-Hung, Patel, Bhaumik, Bonala, Santosh, Manne, Sasikanth, Zhou, Yan, Vadrevu, Surya K., Patel, Jalpa, Peronaci, Marco, Ghouse, Shanawaz, Henske, Elizabeth P., Roegiers, Fabrice, Giannikou, Krinio, Kwiatkowski, David J., Mansouri, Hossein, Markiewski, Maciej M., White, Brandon, Karbowniczek, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705704/ https://www.ncbi.nlm.nih.gov/pubmed/29184052 http://dx.doi.org/10.1038/s41467-017-01845-1

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