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Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
Despite increased use of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) for drug development and disease modeling studies, methods to generate large, functional heart tissues for human therapy are lacking. Here we present a “Cardiopatch” platform for 3D culture and maturation...
Autores principales: | Shadrin, Ilya Y., Allen, Brian W., Qian, Ying, Jackman, Christopher P., Carlson, Aaron L., Juhas, Mark E., Bursac, Nenad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705709/ https://www.ncbi.nlm.nih.gov/pubmed/29184059 http://dx.doi.org/10.1038/s41467-017-01946-x |
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