Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Crescentic rapidly progressive glomerulonephritis (RPGN) represents the most aggressive form of acquired glomerular disease. While most therapeutic approaches involve potentially toxic immunosuppressive strategies, the pathophysiology remains incompletely understood. Podocytes are glomerular epithel...

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Detalles Bibliográficos
Autores principales: Henique, Carole, Bollée, Guillaume, Loyer, Xavier, Grahammer, Florian, Dhaun, Neeraj, Camus, Marine, Vernerey, Julien, Guyonnet, Léa, Gaillard, François, Lazareth, Hélène, Meyer, Charlotte, Bensaada, Imane, Legrès, Luc, Satoh, Takashi, Akira, Shizuo, Bruneval, Patrick, Dimmeler, Stefanie, Tedgui, Alain, Karras, Alexandre, Thervet, Eric, Nochy, Dominique, Huber, Tobias B., Mesnard, Laurent, Lenoir, Olivia, Tharaux, Pierre-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705755/
https://www.ncbi.nlm.nih.gov/pubmed/29184126
http://dx.doi.org/10.1038/s41467-017-01885-7

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