ΔNp73 regulates the expression of the multidrug-resistance genes ABCB1 and ABCB5 in breast cancer and melanoma cells - a short report

PURPOSE: Multidrug resistance (MDR) is a major cause of treatment failure. In cancer cells, MDR is often caused by an increased efflux of therapeutic drugs mediated by an up-regulation of ATP binding cassette (ABC) transporters. It has previously been shown that oncogenic ΔNp73 plays an important ro...

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Detalles Bibliográficos
Autores principales: Sakil, Habib A. M., Stantic, Marina, Wolfsberger, Johanna, Brage, Suzanne Egyhazi, Hansson, Johan, Wilhelm, Margareta T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705756/
https://www.ncbi.nlm.nih.gov/pubmed/28677036
http://dx.doi.org/10.1007/s13402-017-0340-x

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