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Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines

Epstein-Barr virus (EBV), an oncogenic herpesvirus, infects and transforms primary B cells into immortal lymphoblastoid cell lines (LCLs), providing a model for EBV-mediated tumorigenesis. EBV transformation stimulates robust homotypic aggregation, indicating that EBV induces molecules that mediate...

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Detalles Bibliográficos
Autores principales: Grossman, Lisa, Chang, Chris, Dai, Joanne, Nikitin, Pavel A., Jima, Dereje D., Dave, Sandeep S., Luftig, Micah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705804/
https://www.ncbi.nlm.nih.gov/pubmed/29202043
http://dx.doi.org/10.1128/mSphere.00305-17