Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) constitutes the most inherited kidney disease. Mutations in the PKD1 and PKD2 genes, encoding the polycystin 1 and polycystin 2 Ca(2+) ion channels, respectively, result in tubular epithelial cell-derived renal cysts. Recent clinical studies demon...

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Detalles Bibliográficos
Autores principales: Ishimoto, Yu, Inagi, Reiko, Yoshihara, Daisuke, Kugita, Masanori, Nagao, Shizuko, Shimizu, Akira, Takeda, Norihiko, Wake, Masaki, Honda, Kenjiro, Zhou, Jing, Nangaku, Masaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705822/
https://www.ncbi.nlm.nih.gov/pubmed/28993480
http://dx.doi.org/10.1128/MCB.00337-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705822/
https://www.ncbi.nlm.nih.gov/pubmed/28993480
http://dx.doi.org/10.1128/MCB.00337-17

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