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Independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy

PURPOSE: The aim of this study is to describe a phantom designed for independent examination of a source position in brachytherapy that is suitable for inclusion in an external auditing program. MATERIAL AND METHODS: We developed a phantom that has a special design and a simple mechanism, capable of...

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Autores principales: Okamoto, Hiroyuki, Nakamura, Satoshi, Nishioka, Shie, Iijima, Kotaro, Wakita, Akihisa, Abe, Yukinao, Tohyama, Naoki, Kawamura, Shinji, Minemura, Toshiyuki, Itami, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705831/
https://www.ncbi.nlm.nih.gov/pubmed/29204169
http://dx.doi.org/10.5114/jcb.2017.70952
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author Okamoto, Hiroyuki
Nakamura, Satoshi
Nishioka, Shie
Iijima, Kotaro
Wakita, Akihisa
Abe, Yukinao
Tohyama, Naoki
Kawamura, Shinji
Minemura, Toshiyuki
Itami, Jun
author_facet Okamoto, Hiroyuki
Nakamura, Satoshi
Nishioka, Shie
Iijima, Kotaro
Wakita, Akihisa
Abe, Yukinao
Tohyama, Naoki
Kawamura, Shinji
Minemura, Toshiyuki
Itami, Jun
author_sort Okamoto, Hiroyuki
collection PubMed
description PURPOSE: The aim of this study is to describe a phantom designed for independent examination of a source position in brachytherapy that is suitable for inclusion in an external auditing program. MATERIAL AND METHODS: We developed a phantom that has a special design and a simple mechanism, capable of firmly fixing a radiochromic film and tandem-ovoid applicators to assess discrepancies in source positions between the measurements and treatment planning system (TPS). Three tests were conducted: 1) reproducibility of the source positions (n = 5); 2) source movements inside the applicator tube; 3) changing source position by changing curvature of the transfer tubes. In addition, as a trial study, the phantom was mailed to 12 institutions, and 23 trial data sets were examined. The source displacement ΔX and ΔY (reference = TPS) were expressed according to the coordinates, in which the positive direction on the X-axis corresponds to the external side of the applicator perpendicular to source transfer direction Y-axis. RESULTS: Test 1: The 1σ fell within 1 mm irrespective of the dwell positions. Test 2: ΔX were greater around the tip of the applicator owing to the source cable. Test 3: All of the source position changes fell within 1 mm. For postal audit, the mean and 1.96σ in ΔX were 0.8 and 0.8 mm, respectively. Almost all data were located within a positive region along the X-axis due to the source cable. The mean and 1.96σ in ΔY were 0.3 and 1.6 mm, respectively. The variance in ΔY was greater than that in ΔX, and large uncertainties exist in the determination of the first dwell position. The 95% confidence limit was 2.1 mm. CONCLUSIONS: In HDR brachytherapy, an effectiveness of independent source position assessment could be demonstrated. The 95% confidence limit was 2.1 mm for a tandem-ovoids applicator.
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spelling pubmed-57058312017-12-04 Independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy Okamoto, Hiroyuki Nakamura, Satoshi Nishioka, Shie Iijima, Kotaro Wakita, Akihisa Abe, Yukinao Tohyama, Naoki Kawamura, Shinji Minemura, Toshiyuki Itami, Jun J Contemp Brachytherapy Original Paper PURPOSE: The aim of this study is to describe a phantom designed for independent examination of a source position in brachytherapy that is suitable for inclusion in an external auditing program. MATERIAL AND METHODS: We developed a phantom that has a special design and a simple mechanism, capable of firmly fixing a radiochromic film and tandem-ovoid applicators to assess discrepancies in source positions between the measurements and treatment planning system (TPS). Three tests were conducted: 1) reproducibility of the source positions (n = 5); 2) source movements inside the applicator tube; 3) changing source position by changing curvature of the transfer tubes. In addition, as a trial study, the phantom was mailed to 12 institutions, and 23 trial data sets were examined. The source displacement ΔX and ΔY (reference = TPS) were expressed according to the coordinates, in which the positive direction on the X-axis corresponds to the external side of the applicator perpendicular to source transfer direction Y-axis. RESULTS: Test 1: The 1σ fell within 1 mm irrespective of the dwell positions. Test 2: ΔX were greater around the tip of the applicator owing to the source cable. Test 3: All of the source position changes fell within 1 mm. For postal audit, the mean and 1.96σ in ΔX were 0.8 and 0.8 mm, respectively. Almost all data were located within a positive region along the X-axis due to the source cable. The mean and 1.96σ in ΔY were 0.3 and 1.6 mm, respectively. The variance in ΔY was greater than that in ΔX, and large uncertainties exist in the determination of the first dwell position. The 95% confidence limit was 2.1 mm. CONCLUSIONS: In HDR brachytherapy, an effectiveness of independent source position assessment could be demonstrated. The 95% confidence limit was 2.1 mm for a tandem-ovoids applicator. Termedia Publishing House 2017-10-19 2017-10 /pmc/articles/PMC5705831/ /pubmed/29204169 http://dx.doi.org/10.5114/jcb.2017.70952 Text en Copyright: © 2017 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Okamoto, Hiroyuki
Nakamura, Satoshi
Nishioka, Shie
Iijima, Kotaro
Wakita, Akihisa
Abe, Yukinao
Tohyama, Naoki
Kawamura, Shinji
Minemura, Toshiyuki
Itami, Jun
Independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy
title Independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy
title_full Independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy
title_fullStr Independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy
title_full_unstemmed Independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy
title_short Independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy
title_sort independent assessment of source position for gynecological applicator in high-dose-rate brachytherapy
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705831/
https://www.ncbi.nlm.nih.gov/pubmed/29204169
http://dx.doi.org/10.5114/jcb.2017.70952
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