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Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?

AIM: The present study aimed to investigate the relation between FACED and BSI scores, which were developed to measure the severity of bronchiectasis, and systemic inflammation in patients with stable bronchiectasis. METHODS: FACED and BSI scores of 117 patients with stable bronchiectasis were calcu...

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Autores principales: Coban, Hikmet, Gungen, Adil Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705887/
https://www.ncbi.nlm.nih.gov/pubmed/29270068
http://dx.doi.org/10.1155/2017/9874068
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author Coban, Hikmet
Gungen, Adil Can
author_facet Coban, Hikmet
Gungen, Adil Can
author_sort Coban, Hikmet
collection PubMed
description AIM: The present study aimed to investigate the relation between FACED and BSI scores, which were developed to measure the severity of bronchiectasis, and systemic inflammation in patients with stable bronchiectasis. METHODS: FACED and BSI scores of 117 patients with stable bronchiectasis were calculated. The correlations between mean scores and CRP levels, leukocyte count, and neutrophil/lymphocyte ratio were investigated. FINDINGS: Mean BSI and FACED scores were 7.2 ± 5.2 and 2.1 ± 1.8, respectively. The severity of bronchiectasis as determined based on BSI and FACED increased significantly with increasing levels of CRP in patients with stable bronchiectasis (p=0.001 and p=0.027, resp.). No significant changes were found in leukocyte count (p=0.72 and p=0.09, resp.) and N/L ratio (p=0.45 and p=0.71, resp.). BSI and FACED scores were significantly correlated with CRP but not with leukocyte count or N/L ratio. CONCLUSION: In patients with stable bronchiectasis who are evaluated based on FACED and BSI scores, CRP can be a useful biomarker as a direct indicator of the severity of systemic inflammation.
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spelling pubmed-57058872017-12-21 Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? Coban, Hikmet Gungen, Adil Can Can Respir J Research Article AIM: The present study aimed to investigate the relation between FACED and BSI scores, which were developed to measure the severity of bronchiectasis, and systemic inflammation in patients with stable bronchiectasis. METHODS: FACED and BSI scores of 117 patients with stable bronchiectasis were calculated. The correlations between mean scores and CRP levels, leukocyte count, and neutrophil/lymphocyte ratio were investigated. FINDINGS: Mean BSI and FACED scores were 7.2 ± 5.2 and 2.1 ± 1.8, respectively. The severity of bronchiectasis as determined based on BSI and FACED increased significantly with increasing levels of CRP in patients with stable bronchiectasis (p=0.001 and p=0.027, resp.). No significant changes were found in leukocyte count (p=0.72 and p=0.09, resp.) and N/L ratio (p=0.45 and p=0.71, resp.). BSI and FACED scores were significantly correlated with CRP but not with leukocyte count or N/L ratio. CONCLUSION: In patients with stable bronchiectasis who are evaluated based on FACED and BSI scores, CRP can be a useful biomarker as a direct indicator of the severity of systemic inflammation. Hindawi 2017 2017-11-15 /pmc/articles/PMC5705887/ /pubmed/29270068 http://dx.doi.org/10.1155/2017/9874068 Text en Copyright © 2017 Hikmet Coban and Adil Can Gungen. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Coban, Hikmet
Gungen, Adil Can
Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?
title Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?
title_full Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?
title_fullStr Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?
title_full_unstemmed Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?
title_short Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?
title_sort is there a correlation between new scoring systems and systemic inflammation in stable bronchiectasis?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705887/
https://www.ncbi.nlm.nih.gov/pubmed/29270068
http://dx.doi.org/10.1155/2017/9874068
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