Cargando…
Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis?
AIM: The present study aimed to investigate the relation between FACED and BSI scores, which were developed to measure the severity of bronchiectasis, and systemic inflammation in patients with stable bronchiectasis. METHODS: FACED and BSI scores of 117 patients with stable bronchiectasis were calcu...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705887/ https://www.ncbi.nlm.nih.gov/pubmed/29270068 http://dx.doi.org/10.1155/2017/9874068 |
_version_ | 1783282116318986240 |
---|---|
author | Coban, Hikmet Gungen, Adil Can |
author_facet | Coban, Hikmet Gungen, Adil Can |
author_sort | Coban, Hikmet |
collection | PubMed |
description | AIM: The present study aimed to investigate the relation between FACED and BSI scores, which were developed to measure the severity of bronchiectasis, and systemic inflammation in patients with stable bronchiectasis. METHODS: FACED and BSI scores of 117 patients with stable bronchiectasis were calculated. The correlations between mean scores and CRP levels, leukocyte count, and neutrophil/lymphocyte ratio were investigated. FINDINGS: Mean BSI and FACED scores were 7.2 ± 5.2 and 2.1 ± 1.8, respectively. The severity of bronchiectasis as determined based on BSI and FACED increased significantly with increasing levels of CRP in patients with stable bronchiectasis (p=0.001 and p=0.027, resp.). No significant changes were found in leukocyte count (p=0.72 and p=0.09, resp.) and N/L ratio (p=0.45 and p=0.71, resp.). BSI and FACED scores were significantly correlated with CRP but not with leukocyte count or N/L ratio. CONCLUSION: In patients with stable bronchiectasis who are evaluated based on FACED and BSI scores, CRP can be a useful biomarker as a direct indicator of the severity of systemic inflammation. |
format | Online Article Text |
id | pubmed-5705887 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-57058872017-12-21 Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? Coban, Hikmet Gungen, Adil Can Can Respir J Research Article AIM: The present study aimed to investigate the relation between FACED and BSI scores, which were developed to measure the severity of bronchiectasis, and systemic inflammation in patients with stable bronchiectasis. METHODS: FACED and BSI scores of 117 patients with stable bronchiectasis were calculated. The correlations between mean scores and CRP levels, leukocyte count, and neutrophil/lymphocyte ratio were investigated. FINDINGS: Mean BSI and FACED scores were 7.2 ± 5.2 and 2.1 ± 1.8, respectively. The severity of bronchiectasis as determined based on BSI and FACED increased significantly with increasing levels of CRP in patients with stable bronchiectasis (p=0.001 and p=0.027, resp.). No significant changes were found in leukocyte count (p=0.72 and p=0.09, resp.) and N/L ratio (p=0.45 and p=0.71, resp.). BSI and FACED scores were significantly correlated with CRP but not with leukocyte count or N/L ratio. CONCLUSION: In patients with stable bronchiectasis who are evaluated based on FACED and BSI scores, CRP can be a useful biomarker as a direct indicator of the severity of systemic inflammation. Hindawi 2017 2017-11-15 /pmc/articles/PMC5705887/ /pubmed/29270068 http://dx.doi.org/10.1155/2017/9874068 Text en Copyright © 2017 Hikmet Coban and Adil Can Gungen. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Coban, Hikmet Gungen, Adil Can Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? |
title | Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? |
title_full | Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? |
title_fullStr | Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? |
title_full_unstemmed | Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? |
title_short | Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? |
title_sort | is there a correlation between new scoring systems and systemic inflammation in stable bronchiectasis? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705887/ https://www.ncbi.nlm.nih.gov/pubmed/29270068 http://dx.doi.org/10.1155/2017/9874068 |
work_keys_str_mv | AT cobanhikmet isthereacorrelationbetweennewscoringsystemsandsystemicinflammationinstablebronchiectasis AT gungenadilcan isthereacorrelationbetweennewscoringsystemsandsystemicinflammationinstablebronchiectasis |