Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species

Development of a vaccine to protect against cryptococcosis is a priority given the enormous global burden of disease in at-risk individuals. Using glucan particles (GPs) as a delivery system, we previously demonstrated that mice vaccinated with crude Cryptococcus-derived alkaline extracts were prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Specht, Charles A., Lee, Chrono K., Huang, Haibin, Hester, Maureen M., Liu, Jianhua, Luckie, Bridget A., Torres Santana, Melanie A., Mirza, Zeynep, Khoshkenar, Payam, Abraham, Ambily, Shen, Zu T., Lodge, Jennifer K., Akalin, Ali, Homan, Jane, Ostroff, Gary R., Levitz, Stuart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705919/
https://www.ncbi.nlm.nih.gov/pubmed/29184017
http://dx.doi.org/10.1128/mBio.01872-17

Ejemplares similares

Ejemplares similares