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First cephalosomatic anastomosis in a human model
BACKGROUND: Cephalosomatic anastomosis (CSA) has never been attempted before in man as the transected spinal cords of the body donor and body recipient could not be “fused” back together. Recent advances made this possible. Here, we report on the surgical steps necessary to reconnect a head to a bod...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705925/ https://www.ncbi.nlm.nih.gov/pubmed/29279793 http://dx.doi.org/10.4103/sni.sni_415_17 |
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author | Ren, Xiaoping Li, Ming Zhao, Xin Liu, Zehan Ren, Shuai Zhang, Yafang Zhang, Shide Canavero, Sergio |
author_facet | Ren, Xiaoping Li, Ming Zhao, Xin Liu, Zehan Ren, Shuai Zhang, Yafang Zhang, Shide Canavero, Sergio |
author_sort | Ren, Xiaoping |
collection | PubMed |
description | BACKGROUND: Cephalosomatic anastomosis (CSA) has never been attempted before in man as the transected spinal cords of the body donor and body recipient could not be “fused” back together. Recent advances made this possible. Here, we report on the surgical steps necessary to reconnect a head to a body at the cervical level. METHODS: Full rehearsal of a CSA on two recently deceased human cadavers was performed at Harbin Medical University, Harbin, China. RESULTS: The surgery took 18 hours to complete within the time frame planned for this surgery. Several advances resulted from this rehearsal, including optimization of the surgical steps, sparing of the main nerves (phrenics, recurrent laryngeal nerves), and assessment of vertebral stabilization. CONCLUSION: Several specialties are involved in a full-scale CSA, including neck surgery, vascular surgery, orthopedic surgery, plastic surgery, gastrointestinal surgery, and neurosurgery, as well as the operating staff. This rehearsal confirmed the surgical feasibility of a human CSA and further validated the surgical plan. Education and coordination of all the operating teams and coordination of the operative staff was achieved in preparation for the live human CSA. |
format | Online Article Text |
id | pubmed-5705925 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-57059252017-12-26 First cephalosomatic anastomosis in a human model Ren, Xiaoping Li, Ming Zhao, Xin Liu, Zehan Ren, Shuai Zhang, Yafang Zhang, Shide Canavero, Sergio Surg Neurol Int Head and Spinal Cord Transplantation: Original Article BACKGROUND: Cephalosomatic anastomosis (CSA) has never been attempted before in man as the transected spinal cords of the body donor and body recipient could not be “fused” back together. Recent advances made this possible. Here, we report on the surgical steps necessary to reconnect a head to a body at the cervical level. METHODS: Full rehearsal of a CSA on two recently deceased human cadavers was performed at Harbin Medical University, Harbin, China. RESULTS: The surgery took 18 hours to complete within the time frame planned for this surgery. Several advances resulted from this rehearsal, including optimization of the surgical steps, sparing of the main nerves (phrenics, recurrent laryngeal nerves), and assessment of vertebral stabilization. CONCLUSION: Several specialties are involved in a full-scale CSA, including neck surgery, vascular surgery, orthopedic surgery, plastic surgery, gastrointestinal surgery, and neurosurgery, as well as the operating staff. This rehearsal confirmed the surgical feasibility of a human CSA and further validated the surgical plan. Education and coordination of all the operating teams and coordination of the operative staff was achieved in preparation for the live human CSA. Medknow Publications & Media Pvt Ltd 2017-11-17 /pmc/articles/PMC5705925/ /pubmed/29279793 http://dx.doi.org/10.4103/sni.sni_415_17 Text en Copyright: © 2017 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Head and Spinal Cord Transplantation: Original Article Ren, Xiaoping Li, Ming Zhao, Xin Liu, Zehan Ren, Shuai Zhang, Yafang Zhang, Shide Canavero, Sergio First cephalosomatic anastomosis in a human model |
title | First cephalosomatic anastomosis in a human model |
title_full | First cephalosomatic anastomosis in a human model |
title_fullStr | First cephalosomatic anastomosis in a human model |
title_full_unstemmed | First cephalosomatic anastomosis in a human model |
title_short | First cephalosomatic anastomosis in a human model |
title_sort | first cephalosomatic anastomosis in a human model |
topic | Head and Spinal Cord Transplantation: Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705925/ https://www.ncbi.nlm.nih.gov/pubmed/29279793 http://dx.doi.org/10.4103/sni.sni_415_17 |
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