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Genetically engineered mouse models of craniopharyngioma: an opportunity for therapy development and understanding of tumor biology

Adamantinomatous craniopharyngioma (ACP) is the commonest tumor of the sellar region in childhood. Two genetically engineered mouse models have been developed and are giving valuable insights into ACP biology. These models have identified novel pathways activated in tumors, revealed an important fun...

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Detalles Bibliográficos
Autores principales: Apps, John Richard, Martinez‐Barbera, Juan Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705945/
https://www.ncbi.nlm.nih.gov/pubmed/28414891
http://dx.doi.org/10.1111/bpa.12501